Long believed to be hiding in caves, bin Laden was tracked down in a costly, custom-built hideout not far from a Pakistani military academy.
"Justice has been done," President Barack Obama said in a dramatic announcement at the White House while a crowd cheered outside and hundreds more gathered at ground zero in Manhattan to celebrate the news.
The military operation took mere minutes.
U.S. helicopters ferrying elite counter-terrorism troops into the compound identified by the CIA as bin Laden's hideout -- and back out again in less than 40 minutes. Bin Laden was shot in the head, officials said, after he and his bodyguards resisted the assault.
Three adult males were also killed in the raid, including one of bin Laden's sons, whom officials did not name. One of bin Laden's sons, Hamza, is a senior member of al Qaeda. U.S. officials also said one woman was killed when she was used as a shield by a male combatant, and two other women were injured.